Kieran Clarke Selected Research

Ketosis

1/2022	Evaluation of Acute Supplementation With the Ketone Ester (R)-3-Hydroxybutyl-(R)-3-Hydroxybutyrate (deltaG) in Healthy Volunteers by Cardiac and Skeletal Muscle 31P Magnetic Resonance Spectroscopy.
1/2022	Exogenous d-β-hydroxybutyrate lowers blood glucose in part by decreasing the availability of L-alanine for gluconeogenesis.
7/2021	Exogenous ketosis in patients with type 2 diabetes: Safety, tolerability and effect on glycaemic control.
1/2021	The Effect of Blood Ketone Concentration and Exercise Intensity on Exogenous Ketone Oxidation Rates in Athletes.
1/2020	Diet modulates brain network stability, a biomarker for brain aging, in young adults.
12/2019	Safety and tolerability of sustained exogenous ketosis using ketone monoester drinks for 28 days in healthy adults.
12/2019	A ketone monoester drink reduces the glycemic response to an oral glucose challenge in individuals with obesity: a randomized trial.
1/2019	Beyond RPE: The Perception of Exercise Under Normal and Ketotic Conditions.
1/2019	Nutritional Ketoacidosis During Incremental Exercise in Healthy Athletes.
1/2019	The Mechanisms by Which the Ketone Body D-β-Hydroxybutyrate May Improve the Multiple Cellular Pathologies of Parkinson's Disease.

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Kieran Clarke Research Topics

Disease

24	Heart Failure 01/2020 - 06/2003
20	Hypoxia (Hypoxemia) 01/2022 - 11/2007
15	Ketosis 01/2022 - 12/2015
12	Hypertrophy 05/2015 - 05/2003
11	Type 2 Diabetes Mellitus (MODY) 01/2022 - 06/2003
11	Insulin Resistance 01/2022 - 04/2002
10	Obesity 12/2019 - 02/2008
10	Myocardial Infarction 03/2013 - 06/2003
9	Ischemia 10/2018 - 04/2002
8	Body Weight (Weight, Body) 12/2019 - 03/2012
7	Cardiomegaly (Heart Hypertrophy) 05/2015 - 06/2003
6	Cardiomyopathies (Cardiomyopathy) 03/2015 - 06/2006
5	Heart Diseases (Heart Disease) 01/2020 - 11/2005
5	Weight Loss (Weight Reduction) 01/2018 - 08/2009
4	Starvation 11/2020 - 01/2019
4	Infarction (Infarctions) 11/2013 - 08/2008
3	Parkinson Disease (Parkinson's Disease) 01/2020 - 12/2016
3	Fibrosis (Cirrhosis) 01/2017 - 01/2012
3	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 07/2012 - 01/2005
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 12/2016
2	Cognitive Dysfunction 01/2020 - 12/2009
2	Nervous System Diseases (Neurological Disorders) 01/2019 - 01/2016
2	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 06/2013
2	Metabolic Diseases (Metabolic Disease) 01/2018 - 12/2015
2	Coronary Artery Disease (Coronary Atherosclerosis) 12/2017 - 10/2017
2	Hypertension (High Blood Pressure) 10/2017 - 09/2013
2	Diabetic Cardiomyopathies 12/2016 - 08/2015
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2015 - 10/2006
2	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 06/2015 - 02/2011
2	Cardiovascular Diseases (Cardiovascular Disease) 08/2013 - 06/2003
2	Myocardial Stunning (Stunned Myocardium) 12/2012 - 02/2003
2	Reperfusion Injury 12/2012 - 05/2005
2	Hyperthyroidism 06/2011 - 01/2010
2	Atherosclerotic Plaque (Atheroma) 12/2004 - 12/2004
1	Traumatic Brain Injuries (Traumatic Brain Injury) 06/2022

Drug/Important Bio-Agent (IBA)

23	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 04/2002
23	KetonesIBA 01/2022 - 07/2012
17	Adenosine Triphosphate (ATP)IBA 01/2020 - 04/2002
13	Proteins (Proteins, Gene)FDA Link 10/2018 - 05/2003
12	Oxygen (Dioxygen)IBA 01/2022 - 07/2010
12	Insulin (Novolin)FDA Link 07/2021 - 04/2002
11	Nonesterified Fatty Acids (NEFA)IBA 01/2022 - 11/2004
10	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 01/2010
9	EstersIBA 01/2022 - 08/2012
9	Lactic Acid (Lactate)FDA LinkGeneric 01/2022 - 01/2010
8	Phosphocreatine (Neoton)IBA 10/2018 - 05/2005
8	Phosphates (Orthophosphate)IBA 07/2012 - 06/2003
7	DystrophinIBA 10/2018 - 01/2005
7	Pyruvic Acid (Pyruvate)IBA 06/2017 - 08/2009
6	EnzymesIBA 01/2017 - 01/2010
6	CreatineIBA 03/2013 - 11/2004
4	CarbohydratesIBA 07/2021 - 01/2016
4	Triglycerides (Triacylglycerol)IBA 12/2019 - 01/2016
4	GlycogenIBA 10/2018 - 09/2013
4	GadoliniumIBA 03/2016 - 08/2011
4	LipidsIBA 12/2015 - 03/2013
4	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 09/2013 - 07/2006
4	creatine transporterIBA 12/2012 - 02/2005
3	Blood Glucose (Blood Sugar)IBA 01/2022 - 08/2015
3	IronIBA 01/2022 - 03/2015
3	CholesterolIBA 12/2019 - 02/2008
3	Ketone BodiesIBA 01/2019 - 01/2010
3	Uncoupling Protein 3IBA 10/2018 - 05/2011
3	Adenosine (Adenocard)FDA LinkGeneric 10/2018 - 10/2017
3	Oxidoreductases (Dehydrogenase)IBA 06/2017 - 06/2011
3	chenodeoxycholate sulfate conjugate (CDCS)IBA 01/2016 - 04/2012
3	Citrate (si)-Synthase (Synthase, Citrate)IBA 11/2014 - 12/2008
3	CatecholaminesIBA 05/2014 - 09/2010
3	Dobutamine FDA LinkGeneric 03/2012 - 05/2005
3	UtrophinIBA 02/2011 - 01/2005
3	salicylhydroxamic acid (SHAM)IBA 01/2010 - 02/2005
3	Phosphorus (Red Phosphorus)IBA 07/2006 - 04/2002
2	LigandsIBA 01/2019 - 01/2016
2	CytokinesIBA 01/2017 - 01/2016
2	AntioxidantsIBA 01/2017 - 12/2012
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2016 - 01/2016
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 05/2012
2	Peptides (Polypeptides)IBA 03/2015 - 06/2013
2	Transcription Factors (Transcription Factor)IBA 12/2014 - 07/2010
2	Streptozocin (Streptozotocin)FDA Link 09/2013 - 08/2008
2	Indicators and Reagents (Reagents)IBA 08/2011 - 01/2010
2	Adenosine Diphosphate (ADP)IBA 05/2011 - 11/2005
2	LeptinIBA 12/2010 - 02/2008
2	Mitochondrial Uncoupling ProteinsIBA 12/2009 - 11/2004
2	PPAR alphaIBA 10/2006 - 06/2005
2	cysteine and glycine-rich protein 3IBA 06/2006 - 01/2005
2	DesminIBA 06/2006 - 01/2005
2	Cytoskeletal ProteinsIBA 06/2006 - 01/2005
2	Ventricular MyosinsIBA 06/2006 - 05/2005
2	Glucose Transporter Type 4IBA 06/2005 - 04/2002
2	Guanidinoacetate N-Methyltransferase (Guanidinoacetate Methyltransferase)IBA 05/2005 - 11/2004
2	Rosiglitazone (Avandia)FDA Link 06/2003 - 04/2002
1	Alanine (L-Alanine)FDA Link 01/2022
1	FructosamineIBA 07/2021
1	Niacin (Nicotinic Acid)FDA LinkGeneric 11/2020

Therapy/Procedure

12	Therapeutics 06/2022 - 11/2005
5	Ketogenic Diet 07/2021 - 01/2017
4	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 01/2019 - 04/2011
2	Caloric Restriction 01/2019 - 01/2017
2	Intraperitoneal Injections 09/2013 - 06/2011